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Cats but not rats? Humans but not pigs? A study into the molecular mechanism of type 2 diabetes using 2D IR spectroscopy

Wednesday, June 1, 2016, 2:00 PM - 3:00 PM
Martin Zanni, Professor of Chemistry, University of Wisconsin

Aggregation of the human islet amyloid polypeptide (hIAPP or amylin) is closely associated with type 2 diabetes. Using 2D IR spectroscopy and isotope labeling, we have discovered an intermediate in the aggregation pathway in which the central sequen more  »