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Cats but not rats? Humans but not pigs? A study into the molecular mechanism of type 2 diabetes using 2D IR spectroscopy

Wednesday, June 1, 2016, 2:00 PM - 3:00 PM
Martin Zanni, Professor of Chemistry, University of Wisconsin

Aggregation of the human islet amyloid polypeptide (hIAPP or amylin) is closely associated with type 2 diabetes. Using 2D IR spectroscopy and isotope labeling, we have discovered an intermediate in the aggregation pathway in which the central sequen more  »


Thesis Defense

Dirhodium Metallopeptides for Catalytic Protein Modification & Inhibition of Protein-Protein Interactions

Thursday, May 19, 2016, 10:00 AM - 11:00 AM
Farrukh Vohidov, Doctoral Candidate

The fundamental goal of chemical biology is to develop tools for interrogation of the activity and function of biomolecules, ultimately leading to understanding of the inner workings of biological systems. This thesis discusses three contributions to more  »


Total Synthesis as a Rich Source of Unexpected Projects

Monday, May 2, 2016, 4:00 PM - 5:00 PM
Jason Chen, Ph.D., Assisant Professor, Department of Chemistry, Iowa State University

The complex structures and reactions found in natural products total synthesis makes this field not only an inspiration for methodical advances to chemistry, but also a rich source of unexpected projects. Synthesis of breitfussin B by late-stage brom more  »


Thesis Defense

Synthesis, characterization and applications of magnetic multi-metallic oxide nanocrystals

Thursday, April 28, 2016, 9:00 AM - 11:00 AM
Gabriela Escalera, Doctoral Candidate

Nanotechnology has had a great impact in several industries such as medical and electronics, and more recently in the oil and gas industry. In particular, magnetic nanoparticles are receiving great attention in the oil and gas industry because of th more  »


Studies of Natural and Artificial Photosynthesis

Wednesday, April 27, 2016, 4:00 PM - 5:00 PM
Victor Batista, Ph.D., Professor of Chemistry, Yale University

Mechanistic investigations of the water-splitting reaction of the oxygen-evolving complex (OEC) of photosystem II (PSII) are fundamentally informed by structural studies of oxomanganese complexes. Many physical techniques have provided important insi more  »


“The Structure and Mechanisms of State Dependent Neural Correlations”

Tuesday, April 26, 2016, 12:30 PM - 1:30 PM
Krešimir Josi?, Professor, Department of Mathematics, University of Houston

Abstract: Simultaneous recordings from large neural populations are becoming increasingly common. Correlations in neural activity measured in such recordings can reveal important aspects of neural network organization and function. However, estimatin more  »