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Han Xiao
Assistant Professor of Chemistry
Research Statement
Understanding complex biological systems and developing novel therapeutic approaches requires explorations at the interface of chemistry and biology. The focus of our research is the development of various chemical tools that allow us to precisely probe and manipulate biological systems. Our research combines elements from multiple disciplines spanning synthetic chemistry, chemical biology, molecular biology, cancer biology, and immunology.
Bio Statement
Han Xiao is an Assistant Professor of Chemistry, and Biosciences at Rice University. Han was born in 1986 in Changchun, Jilin, China. He obtained his undergraduate degree from the University of Science and Technology of China (USTC) where he graduated with a B.S. in chemistry and an honors degree in physical science. He conducted undergraduate research in Prof. Liu-Zhu Gong’s group, focusing on organic methodology and synthesis of natural products. After graduating from USTC in 2010, Han joined the Ph.D. program at the Scripps Research Institute (TSRI). His thesis work with Prof. Peter G. Schultz focused on expanding the technique of genetically incorporating unnatural amino acids in both prokaryotic and eukaryotic organisms and applying this technique for better cancer therapeutics. In 2015, Han joined the laboratory of Prof. Carolyn R. Bertozzi as a Good Ventures Postdoctoral Fellow of the Life Science Research Foundation at the Stanford University. In his postdoctoral work, he is engaged in the development of novel cancer immune therapy targeting the cell-surface glycans axis of immune modulation. Enzymatic precision glycocalyx editing is able to simultaneously stimulate immune-activating pathways and limit immune-inhibitory pathways within immune cells, thus leading to a promising avenue for cancer immune therapy. In July, Han started his independent research at Rice University. The focus of his research is the development of various chemical biological tools allowing us to understand complex biology system as well as develop novel therapeutic strategies. His research combines elements from multiple disciplines spanning synthetic chemistry, chemical biology, molecular biology, cancer biology and immunology.

Publications

Google Scholar Profile


Department Affiliations
Assistant Professor of Chemistry 
Contact Information
Email: han.xiao@rice.edu 
Office: BioScience Research Collaborative, 317